Lec17 - Muscle I - Lecture 17 Muscle I: Structure and...

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Lecture 17 Muscle I: Structure and Function Reading: Chapter 5, 209 – 221 1 st ed: Chapter 6, 212 - 222 Lecture Outline Structure of Skeletal Muscle Structural Basis of Muscle Contraction Sliding Filament Theory
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Skeletal Muscles are Connected to skeleton – endoskeleton or exoskeleton
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Skeletal muscles usually act as antagonistic pairs - flexors and extensors. Act through contraction.
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Muscles muscle bundles muscle fibers = muscle cells Figure 49.31 Structure of Skeletal Muscle
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Muscle fibers are held together by connective tissue . Blood vessels and nerves are present within the connective tissue. Shape : Few centimeters long but only 20 -100 μ m thick, therefore, diffusion of O 2 and 2
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Embryonic myoblasts (uninucleated cells) fuse to form multinucleated cells.
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Number of fibers is fixed early in life. Myostatin - a cytokine secreted by adult muscle cells inhibits new development of skeletal muscle.
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In adults, increased strength and muscle mass is due to an
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This note was uploaded on 09/12/2010 for the course BIOLOGY 225 taught by Professor Pavgi during the Winter '10 term at University of Michigan.

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Lec17 - Muscle I - Lecture 17 Muscle I: Structure and...

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