exam4_2009_solutions

exam4_2009_solutions - BIOL 4087 Section 3 Fall 2009 Final...

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1 BIOL 4087 Section 3 Fall 2009 Final Exam Dec 10 2009 Part 1: Multiple Choice. Pick the best answer: 5 points each 1) Which of the following phenomena are present in eukaryotic transcription, but not present in prokaryotic transcription? a) Sigma factor guides RNA polymerase to the promoter sequence b) The 30S ribosomal subunit binds to the Shine-Delgarno sequence in the mRNA c) TATA binding protein (TBP) binds to the minor groove in the promotor sequence d) All of the above 2) Which of the following will be affected by a defect in dihydrofolate reductase, resulting in the failure to regenerate tetrahydrofolate from dihydrofolate? a) Methylation of DNA b) Synthesis of deoxyribonucleotides from ribonucleotides c) The formylation of methionine on the intiator tRNA d) All of the above 3) You wish to prepare 14 C-labeled purines by growing bacteria in a medium containing a suitably labeled precursor. The only precursors available are all uniformly labeled to the same specific activity per carbon atom. Which of the following amino acids would be the best to use to obtain purine rings that are labeled to the highest specific activity? a) tryptophan b) arginine c) histidine d) glycine 4) Telomerase, the spliceasome and the 30S ribosome subunit share which common characteristic(s)? a) They are multimeric proteins which have two enzyme activities: phosphorylation and trans-amination b) They are complexes of RNA and protein, in which the RNA interacts with the substrate through Watson-Crick base pairing. c) They are single component proteins which have a preference for binding to supercoiled DNA d) None of the above
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2 5) Which of the following phenomena may be at least partly controlled by a noncoding RNA? a) A protein which is ordinarily anchored to a cell membrane is expressed without the membrane-anchoring domain and is secreted into the extracellular medium. b) A peptide bond is formed between two amino acids c) An mRNA that codes for a particular protein is degraded before it can be translated. d)
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This note was uploaded on 09/13/2010 for the course BIOL 4087 taught by Professor Waldrop during the Spring '08 term at LSU.

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exam4_2009_solutions - BIOL 4087 Section 3 Fall 2009 Final...

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