exam4_2009_solutions

exam4_2009_solutions - BIOL 4087 Section 3 Fall 2009 Final...

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1 BIOL 4087 Section 3 Fall 2009 Final Exam Dec 10 2009 Part 1: Multiple Choice. Pick the best answer: 5 points each 1) Which of the following phenomena are present in eukaryotic transcription, but not present in prokaryotic transcription? a) Sigma factor guides RNA polymerase to the promoter sequence b) The 30S ribosomal subunit binds to the Shine-Delgarno sequence in the mRNA c) TATA binding protein (TBP) binds to the minor groove in the promotor sequence d) All of the above 2) Which of the following will be affected by a defect in dihydrofolate reductase, resulting in the failure to regenerate tetrahydrofolate from dihydrofolate? 3) You wish to prepare 14 C-labeled purines by growing bacteria in a medium containing a suitably labeled precursor. The only precursors available are all uniformly labeled to the same specific activity per carbon atom. Which of the following amino acids would be the best to use to obtain purine rings that are labeled to the highest specific activity? 4) Telomerase, the spliceasome and the 30S ribosome subunit share which common characteristic(s)?
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