Chapter_31

Chapter_31 - Chapter 31 Control edit Master subtitle Click...

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Click to edit Master subtitle style 9/14/10 Chapter 31 Control of Gene Expression Pages 892-905, 913-916
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9/14/10 Gene expression is usually mediated by levels of Prokaryotes Expression in response to environmental signals/needs Eukaryotes Hormones/growth factors Cellular differentiation
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9/14/10 Operons contain regulatory sites for sets of related i=inducer p=promo ter o=operat or
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9/14/10 The lac operon
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9/14/10 DNA binding proteins: the Lac repressor Dimer binds inverted repeat DNA Sequence specific recognition Helix-turn helix motif
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9/14/10 Proteins can also stimulate transcription CAP: catabolic activator protein CRP: cAMP response protein Stimulates transcription of lactose and arabinose metabolizing proteins ~50fold Gene expression is maximal in the presence of allolactose and cAMP
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9/14/10 Three common eukaryotic DNA-binding motifs Zinc finger
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9/14/10 Special features of eukaryotic regulation of Size: 12-300 Mb, 6-25 thousand proteins Cell differentiation Related genes are spread through genome
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Chapter_31 - Chapter 31 Control edit Master subtitle Click...

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