assignment 1

assignment 1 - BILD 3 Summer Session II Dr. Reuther...

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1 BILD 3 Summer Session II Dr. Reuther Assignment #1 Evolution and Hardy-Weinberg equilibrium i 1. Direct your web browser to http://www.gsoftnet.us/GSoft.html . Download Selection 3.2 for your operating system and install it. This software is compressed and your computer will be unable to open the file without decompression software. If your computer does not have decompression software, then here are links to free software for Macs and PCs: Mac : The Unarchiver ( http://wakaba.c3.cx/s/apps/unarchiver.html ) PC: 7zip ( http://www.7-zip.org/ ) Install the proper software for your operating system and use it to decompress the Selection 3.2 software. 2. Read the instruction manual (included in the download). 3. What are the basic assumptions of a population in Hardy-Weinberg equilibrium?
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2 4. If a population is in Hardy-Weinberg equilibrium, then at what value should each of the following parameters be set: Relative fitness for AA: Aa: aa: Population size: Mutation rates: A>a: a>A: Migration rate: Set the simulation to run at the parameters you just listed above. Run the simulation with 5 different initial allele frequencies. You can change the initial allele frequency by adjusting the tab along the y-axis. Run simulations 3 times for each initial allele frequency. How does allele frequency evolve over 500 generations? How is this affected by the initial allele frequency? MUTATION Mutations are chemical changes in the genetic material. Experiments have shown that they do not, as a rule, occur as a response to the needs of the organism. But mutation is important because it provides the raw material (new alleles) for natural selection. It is also
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3 possible that mutation could be an evolutionary force in its own right. That is, if it were consistently in the same direction, could cause major changes in allele frequency. Explore the strength of mutation as an evolutionary force by running some simulations
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assignment 1 - BILD 3 Summer Session II Dr. Reuther...

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