Lecture_20_4-8-10-PDF_41577

Lecture_20_4-8-10-PDF_41577 - Amino Acid Metabolism(Lec...

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Amino Acid Metabolism (Lec 18-21) 4. Breakdown of Amino Acids 5. Amino acid biosynthesis 6. Other products of amino acid metabolism 7. Nitrogen fixation Lec 20 Lec 21
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The carbon atoms of degraded amino acids emerge as major metabolic intermediates. Degradation of the 20 amino acids funnel into 7 metabolic intermediates Breakdown of amino acids 1. Acetyl CoA 2. Acetoacetate 3. Pyruvate 4. α -Ketoglutarate 5. Succinyl CoA 6. Fumarate 7. Oxaoloacetate
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Breakdown of amino acids: overview Glucogenic Glucose precursors Ketogenic Fatty acids Ketone bodies precursoes
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Both Isoleucine (I) Phenylalanine (F) Tryptophan (W) Tyrosine (Y) Ketogenic Leucine (L) Lysine (K) Glucogenic Serine (S) Threonine (T) Aspartic acid (D) Glutamic acid (E) Asparagine (N) Glutamine (Q) Glycine (G) Alanine (A) Valine (V) Proline (P) Histidine (H) Arginine (R) Methionine (M) Cysteine (C)
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