AnSci_lecture_12-01-08_copy[1] - AnSci 20:53:00 Immunology...

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AnSci 16/12/2008 20:53:00 Immunology people who had mild brushes with particular diseases, appeared to generate  some protection against some subsequent exposure o antiquity 1300s to 1700s smallpox was devastating o 2 known repositories of virulent smallpox o successful 1 eradication o spread rapidly o handlers of corpses were at risk of contacting o Jenner (Great Britain) noticed that a segment of the population  seemed to be immune milkmaids through extended contact with cows, contracted cowpox still got disfiguring pussy eruptions of skin Jenner collected the puss from a milkmaid infected with cowpox then persuaded a farmer that he (jenner) could inoculate the  farmers son from smallpox Jenner put the puss from cowpox into the boy-who got a mild  case of it Then exposed him to smallpox—the boy didn’t get it vaccination was coined “virus” too over 200 years ago about 100 years ago, Pasteur was studying chicken cholera
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o studied time-course of onset of symptoms o at one stage he vaccinated clean chickens with what he thought was  the virulent form of chicken cholera, but it was old and they didn’t get  sick o by using the less potent form of the organism first, he established  protection o subsequently became accepted that immunized animals had  something in their blood that fights protection and helps fight disease Immune Protection innate (inborn) immune system-some degree of protection
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This note was uploaded on 09/18/2010 for the course ANSC 2400 taught by Professor Parks during the Fall '09 term at Cornell.

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AnSci_lecture_12-01-08_copy[1] - AnSci 20:53:00 Immunology...

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