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12_pdfsam_apluspreptt1pkg - ± Symptoms • Ataxia(problems...

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± Terminal stage Astasia: inability to stand Severe ataxia, tremor, dysarthria Difficulty swallowing (dysphagia) Death ± Cerebellar dysfunction is the cause of these conditions Fatal Familial Insomnia (FFI) ± Autosomal dominant inherited disease ± Caused by a mutation in the prion gene; asparagine-178 is replaced by aspartic acid ± Plaques to develop in the thalamus (thalamus is responsible for regulation of sleep) ± Symptoms Insomnia, rapid weight loss Panic attacks, phobias, hallucinations Dementia, turning mute Death Gerstmann-Sträussler-Scheinker syndrome (GSS) ± Autosomal dominant inherited disease ± Genetic change is required for the development of the disease; a change in codon 102 from proline to leucine in the prion protein gene ± Progressive spinocerebellar degeneration and accumulation of plaques in the cerebellum
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Unformatted text preview: ± Symptoms • Ataxia (problems with movement and balance) • Dementia • Death 7. Hepatitis A Virus 1. List of Hepatitis Viruses GROUP VIRUS PICORNA Hepatitis A (HAV) 2. Transmission VIRUS MODES OF TRANSMISSION HAV · Oral-fecal · Common-source outbreaks arise from fecally contaminated water or food such as oysters grown in polluted water and eaten raw · HAV is rarely transmitted via the blood 3. Clinical Symptoms ± The clinical manifestations of hepatitis are virtually the same, regardless of which hepatitis virus is the cause. Common symptoms include: • Fever • Anorexia, nausea, vomiting • Jaundice • Coca-cola urine • RUQ (right upper quarter) pain © 2006. A+PREP, Inc....
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