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13_pdfsam_apluspreptt1pkg - Hand-foot-and-mouth disease:...

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Elevated serum bilirubin levels Elevated liver enzyme levels, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ± HAV and HEV infections never become chronic, whereas HBV, HCV, and HDV cause chronic liver diseases. . ± HAV and HBV commonly cause rash 4. History of Infection HAV ± Most infections with HAV are symptomatic, and up to 2/3 may produce jaundice (icteric) ± Virus appears in the feces 2 weeks before the appearance of symptoms 8. 7-STEP Clinical Virology Summary 1 1. Coxsackie Meningitis, Herpangia, Hand-foot-and-mouth disease, Rash, Pleurodynia, Myocarditis, Pericarditis, Common cold, Conjunctivitis ± Group A viruses have a predilection for skin and mucous membranes ± Group B viruses cause diseases in various organs such as the heart, pleura, pancreas, and liver ± Fever, rash, flu-like symptoms ± Central Nervous System Meningitis, encephalitis Paralysis similar to poliomyelitis ± Skin Herpangia: fever, sore throat, tender vesicles in the oropharynx
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Unformatted text preview: Hand-foot-and-mouth disease: vesicular rash on the hands and feet, and ulcerations in the mouth, mainly in children Herpes-like vesicular rashes, Rubella-like rashes ± Striated muscles Pleurodynia (a.k.a. Bornholm disease; “devil’s grip”): fever and severe chest pain due to infections of the diaphragm Chronic Fatigue Syndrome ± Heart Myocarditis, pericarditis, myopericarditis: fever, chest pain, congestive failure; fatal in neonates ± Pancreas Virus can cause pancreatic damage and is suspected to have a role in juvenile diabetes (type I insulin-dependent diabetes mellitus) ± Gastrointestinal tract Gastroenteritis, acute abdominal pain like appendicitis; diarrhea is not frequent ± Respiratory tract Common cold, upper and lower respiratory tract infections, pneumonia ± Eye Conjunctivitis ± Others Polymyositis (inflammation of muscles) Neonatal infections © 2006. A+PREP, Inc....
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This note was uploaded on 09/19/2010 for the course CSB CSB351 taught by Professor Ab during the Spring '09 term at University of Toronto.

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