5. Infections with Aphtoviruses, which are the cause of hand-foot-and-mouth disease in tropics, can be prevented by formalin-inactivated vaccine Select the best answer: A. None of the above B. 1, 2, 3 C. 1, 4 D. 3 E. 3, 5 11. Which statement(s) is/are true about isolation and purification of viruses? 1. The magnitude of the centrifugal force is proportional to the molecular weight of viruses, angular velocity, and the square of the radial distance from axis of rotation to viral particles 2. If two viruses, one with spherical shape and the other with rod-shape, have the same molecular weight, the spherical virus will have the lower sedimentation coefficient 3. If Tobacco Mosaic Virus (TMV) consists of 95% protein and 5% RNA, and if Brome Mosaic Virus (BMV) consists of 80% protein and 20% RNA, then BMV sediments in the upper layer and TMV sediments in the lower layer in Equilibrium Centrifugation 4. If the sedimentation coefficient (S) is 160S for Polioviruses and 80S for BMV, then Polioviruses sediment in the upper layer and BMV sediments in the lower
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