2K - Net ID _ KEY A_ BIOBM3310 Quiz 2a 9/16/09 1. (7 pts)...

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Net ID _ KEY A _ BIOBM3310 Quiz 2a 9/16/09 1. (7 pts) The Ramachandran Map on the right is consistent with: T / F Membrane proteins having different steric hindrance compared to water-soluble proteins T / F Gly residues having a wide range of allowed φ , ψ values T / F Only a small fraction of the φ , ψ values from 0 to 360 o are observed in real proteins T / F φ , ψ values for AA in type I and type II turns not appearing on the map T / F A range of φ , ψ values, not just one precise value, is found for β -sheets T / F For a typical protein, many more φ , ψ values can be observed for the smaller AA residues T / F On the map shown, the φ , ψ values for collagen show up in the upper dark region 2. (7 pts) Draw ONLY THE SIX BONDED ATOMS that are constrained to lie in a plane because of the properties of the peptide bond. Draw no other atoms . Label any C α . Show with an arrow and a label the bond that allows the φ rotation, and the bond that allows the ψ rotation. Show with an arrow labeled "PARTIAL" the one bond (not a carbonyl) that has partial double bond character. 3. (11 pts) Match the left column with the best right column description. Use each right column letter ONCE. J _ comparison with proteins of already known function A. has weak directional constraint I _ a protein + its prosthetic group B. membrane-bound protein E _ disrupts an alpha helix C. special short sequence of AA K _ must be closely related to another protein D. amphipathic helix F _ highly directional interaction of Phe-Phe E. proline D _ nonpolar AA point toward protein interior F. ring stacking C _ signal to import a protein into the nucleus G. a protein crystal G _ is approximately 50% water H. zinc finger H _ can be recognized from primary structure I. holoprotein A _ Lys + sidechain binding to carbonyl group J. do this with a new AA sequence B _ nonpolar AA are on the outside
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This note was uploaded on 09/19/2010 for the course BIOBM 3310 taught by Professor Feigenson,gw during the Fall '07 term at Cornell University (Engineering School).

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2K - Net ID _ KEY A_ BIOBM3310 Quiz 2a 9/16/09 1. (7 pts)...

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