# 4K - Net ID_KEY A QUIZ 4a 1(12 pts Draw O2 binding graphs...

This preview shows pages 1–2. Sign up to view the full content.

D Net ID ____KEY A _____ QUIZ 4a 9/30/09 1. (12 pts) Draw O 2 binding graphs , LABEL THE AXES . Show oxygen binding, not the binding of any other molecules. Write two numerical values including units if any ,on each axis . Label as A, B, C, D, E showing: A. adult Hb, without BPG B. adult Hb + BPG C. Hb that has been dissociated into individual, separated α and β chains. D. Hb + BPG with 2 CO (carbon monoxide) bound E. fetal Hb (+ BPG) 2. (4 pts) Name two negative allosteric effectors of Hb: _ BPG ____ and __ H+ ____ CO2 ALSO OK Name two positive allosteric effectors of Hb: __ O2 ___ and ___ CO ____ 3. (4 pts) Circle T if true, F if false: T F The III structure of Hb α chain, Hb β chain, and Mb look very much the same. T F The I structure of Hb α chain, Hb β chain, and Mb look very much the same. T F Like Hb, Mb changes its oxygen binding when pH changes, as described by the Bohr Effect. T F Hb + BPG has a higher Hill coefficient for oxygen binding than does Mb at all physiological pO 2 . 4. (4 pts) The equilibrium constant K eq for the binding of O 2 to Mb is 2 x 10 6 M -1 , where K eq = [MbO 2 ]/[Mb][O 2 ] . The rate constant for combination of O 2 with Mb is 1 x 10 7 M -1 sec -1 . What is the rate constant for dissociation of O 2 from Mb? K

This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

### Page1 / 3

4K - Net ID_KEY A QUIZ 4a 1(12 pts Draw O2 binding graphs...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document
Ask a homework question - tutors are online