08-27-2010 - Neuron 1. 2. 3. 4. 5. Basic units of the...

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Neuron 1. Basic units of the nervous system 2. More about neurons and neuronal anatomy 3. Receive, integrate, and transmit information 4. Operate through electrical impulses (AP) 5. Communicate with other neurons through chemical signals
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Synapse History about its discovery Synapse structure
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Cajal drawing Golgi’s drawing Cajal and Golgi disagreed on whether spines are real or an artefact of the staining method.
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Golgi’s drawing of the cell types of the human cerebral cortex. Golgi-stained pyramidal neuron from layer 3 of the cerebral cortex of a cat. Background neutral-red stain. Golgi interpreted spines as an artefact of the staining method.
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1.If spines are merely an artefact of a silver precipitate, why do they appear to be confined to the dendrites? Why don’t we see them on axons or on the cell body. 2.Modification of the Golgi method use mercury, rather than silver-based impregnation. Why do we see spines using these methods as well?
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Methylene blue stained pyramidal cortical cells. Cajal’s demonstration of the presence of spines on cortical cells stained with an entirely different technique from Golgi’s method.
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Sherrington – A physiologist showed: 1. Unidirectional flow of information
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This note was uploaded on 09/19/2010 for the course BIOS 286 taught by Professor Murphy during the Fall '06 term at Ill. Chicago.

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08-27-2010 - Neuron 1. 2. 3. 4. 5. Basic units of the...

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