psych180_lec6 - 1. Transmission/presynaptic 2. Release of...

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SYNAPTIC TRANSMISSION
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The Synapse Decision Points in the Central Nervous System 1. The Problem 2. Chemical Mechanisms 3. Transmitters 4. Electrical Events a. Excitation-Depolarization b. Inhibition-Hyperpolarization c. Summation: Temporal and Spatial INTEGRATION .
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1. NEUROTRANSMISSION IS A CHEMICAL PROCESS
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2. Transmission Takes place at the synapse Presynaptic Terminal Bouton Synaptic Cleft Postsynaptic Membrane
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4. Transmitters are stored in small packets (vesicles) in the region of the presynaptic membrane. Released by electrical activity at the synapse
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Binding of neurotransmitters affects The probability of neuronal action
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1. NEUROTRANSMISSION IS A CHEMICAL PROCESS
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ACETYLCHOLINE ACh The neurotransmitter at The neuromuscular junction
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Transmission at the Neuro-Muscular Junction
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Effects of Curare at the Neuromuscular Junction
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Synaptic Transmission Exocytosis
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Normal Neurotransmission
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Unformatted text preview: 1. Transmission/presynaptic 2. Release of transmitter 3. Reception of the transmitter Transmitter release effects the probability of firing the Postsynaptic neuron. The Electrical Signs of Neurotransmission 1. Excitatory Post Synaptic Potential 2. Inhibitory Postsynaptic Potential SYNAPTIC TRANSMISSION Transmission Excitation: E P ost S ynaptic P otential Inhibition: I P ost S ynaptic P otential Integration DECISION Integration at the synapse 1. TEMPORAL SUMMATION 2. SPATIAL SUMMATION 3. ALGEBRAIC SUMMATION OF POSTSYNAPTIC POTENTIALS EPSP + EPSP = 2 X EPSP IPSP + IPSP = 2 X IPSP EPSP = IPSP = 0 The Chemistry of Neurotransmission 1. Synthesis 2. Transport 3. Release 4. Receptor activation 5. Removal/Reuptake THE END 3. Neurotransmission involves the release of a chemical substance....
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psych180_lec6 - 1. Transmission/presynaptic 2. Release of...

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