3209%20Ch7%20slides - rising phase of AP: positive feedback...

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Ch. 7: Neurophysiology: pp 160-166, 170-184, 196-198 •Membrane voltages – Nernst equation •Nerve anatomy •Action potentials Na + and K + channels Threshold, all or none, refractory period Propagation •Synapse: cell-cell interactions/integration
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Nerves and Neurons
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Bouton-synapse Bouton-synapse
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K + channel structure Roderick MacKinnon
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K + channel binds K + selectively
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activation inactivation
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falling phase of AP : inactivation of Na channel + activation of K channel
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Unformatted text preview: rising phase of AP: positive feedback effects on Na channel: AP Propagation AP propagation: myelination cell body axon reception synapse Neurotransmitter release at synapse binds open V io depolarizes Tetanus toxin (spastic paralysis) and botulinum toxin (botox) (flaccid paralysis) ACh esterase blockers Synaptic Integration: threshold vs sub-threshold Synaptic Integration: EPSPs summate Synaptic Integration: EPSP+IPSP cancel Fig. 7.27...
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3209%20Ch7%20slides - rising phase of AP: positive feedback...

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