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kimchee lab hannah'spart - Hexokinase is inhibited by...

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1. Since glycolysis splits glucose to release energy, the main purpose of glycolysis is to produce high-energy electrons for use in the electron transport chain. Pyruvic acid, which is the final product, contains energy that can be harvested. 2. The regulation of glycolysis is important because there are many pathways involved, and lots of ATP production/consumption. Because it would be wasteful for the cell to use free energy in these spontaneous steps, cells need enzyme that will catalyze these steps to turn off glycolysis when the need for ATP is low.The three enzymes used in glycolysis are regulated by hormones that affect their rates of transcription. For instance, phosphofructokinase is allosterically inhibited by ATP itself (so glycolysis is slowed if [ATP] is too high
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Unformatted text preview: ). Hexokinase is inhibited by glucose-6-phosphapte. 3. In the Kreb’s cycle, which requires oxygen, pyruvate moves from the cytoplasm into the mitochondria and converts to acetyl coA. The primary purpose of the Kreb’s cycle is to create high-energy electron carriers NADH and FADH2. Here, carbon dioxide is removed as a waste product(when we exhale). 4. The mitochondrial membrane is important because it is wehre oxidative phosphorylation takes place. Porins, which are channel proteins, allow free movement of ions into the intermembrane space. The five specific integral membrane proteins involved in ATP synthesis in the inner membrane include NADH dehydrogenase, succinate dehydrogenase, cytochrome c reductase, cytochrome c oxidase, and ATP synthase....
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