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Endocrine-Topic1.Sp10

Endocrine-Topic1.Sp10 - Topic#1 Endocrinology 1...

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Topic #1 Endocrinology 1 Organization of Endocrine Lecture 5/18/10 1 Endocrine System as a Regulatory System Comparison to Neural Regulation & Interaction between Nervous and Endocrine Systems. Action of Hormones and How They Regulate Function Hormones Action on Target Site – Distant with transport in blood, Paracrine , Autocrine & Neurocrine Classification of Hormones Based on Structure and Action – Peptides/Proteins , Neuropeptides , Amines & Steroid Hormones , Pheromones Review of Negative and Positive Feedback Endocrine Pancreas – Insulin, Glucagon & Somatostatin. Insulin Role in Absorptive State. Glucagon Role in Post-Absorptive State. Somatostatin Role in Limiting Swings in Blood Glucose when a Large Meal is Consumed. Regulation of Calcium and Phosphate Balance through Vitamin D, (Calcitriol) Parathyroid Hormone (PTH) (and Calcitonin .) Physiology of Bone & Bone Remodeling. Neuroendocrine Regulation Hypothalamus and Pituitary Axis . Action and Regulation of Growth Hormone Action and Regulation of Thyroid Hormones Adrenal Cortex and Steroid Hormones Required Reading for Reproduction: pp. 780 – 796 (Implantation, Gestation, Parturition, & Lactation.
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Topic #1 Endocrinology 2 Introduction 5/18/10 2 Endocrinology Regulation and Homeostasis through the actions of Hormones Hormone Peptides, Steroids and Amines Secreted by ductless glands, Hormones act locally or are carried by the vascular system to other tissues of the body. Neurocrines neurotransmitters having an endocrine action Neurotransmitters released into the circulatory system and have a systemic effect Act on other neurons whose neurotransmitters have a systemic effect
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Topic #1 Endocrinology 3 Comparison of Regulation by the Nervous System and Endocrine System 5/18/10 3 Nervous System Endocrine System Rapid Action – msec to sec. Localized, Specific Site of Action. Communicates using neurotransmitters among neurons & effector tissues Neurotransmitters act locally over very short distances. Slow Action – seconds, minutes, hours, days. Generalized Action on Metabolism, Growth and Development, & Regulation Body Water Communicates through neurosecretions and hormones that can act locally, act on adjacent cells and tissue, or at tissues distant from the site of secretion. Autocrine Effect – acts back on the cells or tissue synthesizing and secreting hormone. Paracrine Effect – acts on adjacent cells or tissues Distal Effect – secretions act carried by the vascular system to tissues distant from site of hormone/neurocrine release. Integration of Neural and Endocrine Regulation occurs between the Hypothalamus and Anterior Pituitary Gland.
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Topic #1 Endocrinology 4 Introduction 5/18/10 4 Classes of Neurosecretions and Hormones Peptides and Small Proteins Neurosecretions, Hormones of the Anterior and Posterior Pituitary Glands, Hormones of the Pancreas and Parafollicular cells of the Thyroid Gland.
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