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Lecture%203-VaccinationforBbSlides

Lecture%203-VaccinationforBbSlides - Human Infectious...

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Human Infectious Diseases Human Infectious Diseases Laboratory Location: NMS 3.236 Email: [email protected] Basic Concepts: Vaccines
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Vaccination Vaccination— underappreciated component of modern medicine Vaccines: nontoxic antigens that are injected, ingested, or inhaled to induce a specific defense response without having to go through the disease process Why aren ʼ t there more vaccines??? Financial (lack of interest from big pharma, lack of funding by governments) Legal (fear of lawsuits) Political (some governments simply do not care) Public is unaware of the benefits of vaccination—out of sight, out of mind We listen to Hollywood, rather than the experts Stars Spar Over Autism, Child Vaccines
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Vaccination Should we vaccinate? According to the Centers for Disease Control, “The decision not to vaccinate is a decision for your child but also a decision for society.” Unlike other medical decisions, refusing vaccinations puts others at risk. Clinical case: Pertussis vaccine refusal in UK In general, be careful of misinformation Example: 1994 Miss America and deafness Good intentions, but lack of knowledge For vaccines administered in the United States, the reduction in incidence of the targeted disease has been at least 96%, and in most cases 99% or higher. In some cases reductions of nearly 100% have made it possible to eradicate the disease (e.g. polio and smallpox) Herd effect: Protection of unvaccinated people in a population where most people are vaccinated due to lessened risk of disease transmission. Herd immunity will be lost if people refuse vaccination, and an outbreak will occur.
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Vaccination Success Stories From Medical Microbiology, 5 th ed. Murray, Rosenthal, and Pfaller. 2005
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