GenCh7answers - 1. The DNA double helix is held together by...

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1. The DNA double helix is held together by two types of bonds, covalent and hydrogen. Covalent bonds occur within each linear strand and strongly bond the bases, sugars, and phosphate groups (both within each component and between components). Hydrogen bonds occur between the two strands and involve a base from one strand with a base from the second in complementary pairing. These hydrogen bonds are individually weak but collectively quite strong. 3. A primer is a short segment of RNA that is synthesized by primase using DNA as a template during DNA replication. Once the primer is synthesized, DNA polymerase then adds DNA to the 3´ end of the RNA. Primers are required because the major DNA polymerase involved with DNA replication is unable to initiate DNA synthesis and, rather, requires a 3´ end. (It is the 3´ -OH group that is required to create the next phosphodiester bond.) The RNA is subsequently removed and replaced with DNA so that no gaps exist in the final product. 4.
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This note was uploaded on 09/25/2010 for the course BIOL 3301 taught by Professor Gunaratne during the Fall '05 term at University of Houston.

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GenCh7answers - 1. The DNA double helix is held together by...

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