ZOO4232 - Lecture 2 Immunology

ZOO4232 Lecture 2 - TheChallenge mortality(Vaccines Annualincidence Mortality Malaria 300500M Schistosomiasis Diarrhea ~4billion Tuberculosis ~9M

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8/31/2009 1 The Challenge Infectious Diseases with high morbidity and mortality: (Vaccines?) Annual incidence Mortality Malaria 300 500M ~2M Schistosomiasis ? 8000 Diarrhea ~4billion ~4M Tuberculosis ~9M ~2M 9M 2M Respiratory ~362M ~4M HIV ~40M ~3M
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8/31/2009 2 The Immune Response: I. Innate immunity The Innate Immune response is defined as that which the body mounts without previous contact with microbe. Is not specific to microbe. Components of innate immunity: outer surface of body (skin) Linings of internal tracts secretion secretions Phagocytic cells (macrophages, neutrophils) and natural killer cells. Soluble blood proteins:Complement Effectors of innate immunity Induction of inflammation at site of infection, release of chemical mediators Interferons complement of chemical mediators – Interferons, complement components … Phagocytosis Complement mediated lysis
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8/31/2009 3 Cells of the Immune System Overview
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8/31/2009 4 Definitions Antigen molecules that react with antibodies or T cells Antibody : plasma proteins produced by B cells that bind specifically to antigens Immunogen : those antigens that can induce specific immune response such as antibody production.
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This note was uploaded on 09/25/2010 for the course ZOO 4232 taught by Professor Kima during the Fall '10 term at University of Florida.

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ZOO4232 Lecture 2 - TheChallenge mortality(Vaccines Annualincidence Mortality Malaria 300500M Schistosomiasis Diarrhea ~4billion Tuberculosis ~9M

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