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stem - Many of the slides from today’s lecture came from...

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Unformatted text preview: Many of the slides from today’s lecture came from David Baltimore’s lecture to the 2007 Bi1 class, which was based on a talk he gave in Physics in 2006. What is a stem cell? • Has the capacity for self- renewal. • Can differentiate into two or more mature cell types. http://www.patentbaristas.com/wp/wp-content/uploads/2007/04/stem-cells.jpg Hematopoietic stem cells Types of Stem Cells Embryonic stem cell has unrestricted potential for differentiation http://www.nature.com/ncb/journal/v3/n9/fig_tab/ncb0901-e205_F1.html Adult stem cells are lineage restricted Policy debate in US • 1969 -- first human in vitro fertilization • 1995 -- Clinton administration said no federal funding if embryos created for research, but would fund research on discarded embryos. Congress passed Dickey Amendment prohibiting federal funding for any research that destroyed any embryo. • 1998 -- privately funded research led to discovery of human embryonic stem cells • 2001 -- Bush administration permitted federal funding of hESC research, but...
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stem - Many of the slides from today’s lecture came from...

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