Anatomy & Physiology I Blood Notes

Anatomy & Physiology I Blood Notes - 1 ,.The...

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1. What is found in a buffy coat in centrifuged blood? The buffy coat in centrifuged blood consists of pale, colorless white blood cells and platelets. The  buffy coat is a very thin layer (accounts for 1% of total blood volume) located between the RBC’s  and plasma in centrifuged blood.  2. What is the definition of hematocryte? Hematocryte is the percentage of total volume occupied by RBC’s. For example, a hematocryte  of 40 means that 40% of the total volume is composed of RBC’s. The normal range for adult  females is 38-46%, and for adult males is 40-54%. Males have a higher percentage due to  testosterone, and lower values in females maybe due to excessive blood loss from menstruation.  Significantly low values indicate anemia, and significantly high values indicate polycythemia.  3. What are pluripotent stem cells?  What cells can they produce? Pluripotent stem cells are mesenchymal cells that have the capacity to develop into several  different types of cells. Stem cells in red bone marrow reproduce themselves, proliferate, and  differentiate into cells that give rise to blood cells, macrophages, reticular cells, mast cells, and  adipocytes. Pluripotent stem cells also produce two further types of stem cells, myeloid stem cells  &   lymphoid   stem  cells.   Myeloid   cells   give   rise   to   RBC’s,   platelets,   monocytes,   neutrophils, 
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eosinophils, and basophils. Lymphoid cells give rise to lymphocyte T and B Cells. 
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