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Unformatted text preview: Role of Corticosterone in Trace and Delay Conditioned Fear-Potentiated Startle in Rats Michael A. Burman, Kathryn L. Hamilton, and Jonathan C. Gewirtz University of Minnesota Hypothesis: in this study, researchers tried to find the role of Corticosterone in trace and delay conditioned fear-potentiated startle in rats. Participants: In this experiment eighty-five male albino Charles River-derived Sprague Dawley rats, weighing between 250 and 400 g were used. Results: only trace fear conditioning was impaired. This suggests that only fear conditioning tasks that are dependent on the dorsal hippocampus require HPA-axis activation in order to be learned. Role of Corticosterone in Trace and Delay Conditioned Fear-Potentiated Startle in Rats Michael A. Burman, Kathryn L. Hamilton, and Jonathan C. Gewirtz University of Minnesota Emotional events often lead to particularly strong memory formation. Corticosterone, the final product of hypothalamic-pituitary-adrenal (HPA)-axis activation, has been suggested to play a critical role in this...
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This note was uploaded on 09/27/2010 for the course PGY 166214 taught by Professor Hudson during the Fall '10 term at SUNY Buffalo.
- Fall '10