MCB150 MT 1

MCB150 MT 1 - 1 Name_ MCB 150 Midterm Exam #1 (100 points...

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1 Name___________________________ MCB 150 Midterm Exam #1 (100 points total) Please write your full name on each page of the exam!! The exam consists of 17 questions (6 pages). Each has a different point count as indicated. Please limit your answer to the space provided. 1. (3 pts) What is apoptosis and how does it differ from necrosis? Which is more likely to trigger inflammation? 2. (4 pts) What is a cytokine? Why do some viruses encode decoy cytokine receptors? 3. (5 pts) From a mouse’s perspective, having a mutation in the TLR4 gene can be either a detriment or a benefit. Explain. 4. (3 pts) What is the difference between a primary lymphoid organ and a secondary lymphoid organ? What is the main primary lymphoid organ in adults for B cells. 5. (5 pts) How many antigen binding sites are found per molecule of: IgA IgG IgM For an IgA and an IgG with the identical antigen binding site, which would bind more tightly to a multivalent ligand? For an IgA and an IgG with the identical antigen binding site, which would bind more tightly to a monovalent ligand?
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2 Name___________________________ 6. (7 pts) For each of the 5 major antibody isotypes indicate whether the following statements apply. IgG IgM IgA IgE IgD Transported across epithelium into secretions Exists in a membrane form only Triggers Mast cell degranulation The earliest Ig secreted after infection Transported across the placenta Present at lowest concentration in blood Good at fixing complement 7. (4 pts) For each of the following conditions indicate whether you would expect a precipitate to form? a.Polyclonal antibody mixed with a multivalent antigen
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This note was uploaded on 09/29/2010 for the course MCB 150 taught by Professor Coscey during the Spring '08 term at Berkeley.

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MCB150 MT 1 - 1 Name_ MCB 150 Midterm Exam #1 (100 points...

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