Study questions for lecture 3 and readings

Study questions for lecture 3 and readings - S tudy...

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Study questions for Exam 1: Week 2 These question highlight important information in lecture as well as the chapter readings What conclusions can you draw soley from the results of the ZP3 knockout? Why can’t you draw any conclusions about whether or not ZP3 is essential for sperm binding from these results? What conclusions can you draw from the humanized ZP3 experiment? Which experimental observations provide evidence that sperm bind to ZP3? What experimental data provide evidence that the carbohydrate on ZP3, is essential for sperm binding to the zona pellucida? If the mom is ZP3 +/- and the dad is ZP3 +/- will they have offspring? Why or why not? If a female has an autoimmune disorder that results in her producing antibodies that recognize ZP3, how will this affect her fertility? If an egg is lacking the zona pellucida, what genes could be mutated in the mother? What is a transcription factor? How do transcription factors regulate (activate or repress) gene expression? What is an enhancer? Why is Figlia called a bHLH transcription factor? If a mother carries a mutation in Figlia, she has ovarian failure? Based on
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Study questions for lecture 3 and readings - S tudy...

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