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Study questions Lectures 6 and 7

Study questions Lectures 6 and 7 - Study questions Lectures...

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Study questions Lectures 6 and 7 Which cells in the compacted morula or early and late blastocysts will express Cdx2, Oct4, Nanog, and Gata6? How will expression of these genes affect cell differentiation in the pre-implantation mouse embryo? How will loss of function mutations in these genes affect cell differentiation in the pre- implantation mouse embryo? How will overexpression of these genes affect differentiation of ES cells? How does expression of Cdx2 in the trophoblast affect expression of Oct4 and Nanog in the trophoblast cells? How does expression of Oct4 in the inner cell mass affect expression of Cdx2 in the inner cell mass? How does expression of Gata6 in the primitive endoderm affect expression of Nanog in the primitive endoderm? How does expression of Nanog in the primitive endoderm affect expression of Gata6? How does the polarity of the outer cells help to specify the fate of the trophoblast cells?
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