Drug History - Harpp The World of Chemistry 183 (170) DRUGS...

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1 1 The World of Chemistry 183 (170) DRUGS 2 Harpp 212 Otto Maass [email protected] [email protected] [email protected] 110 Otto Maass 3 3 SEPT. 7 INTRODUCTION/DRUG HISTORY I SEPT. 14 DRUG HISTORY II/PAIN RELIEVERS SEPT. 21 PAIN & ANESTHETICS SEPT. 28 TOXICOLOGY OCT. 4 MIDTERM I- (Mon.) coverage to end of Oct. 28 TH OCT. 5 ALLERGIES OCT. 12 STOMACH CHEMISTRY/ANTIBIOTICS OCT. 19 SPECIAL PRESENTATION –THE AMAZING RANDI (King of Skeptics) OCT. 26 HEART CHEMISTRY/MENTAL ILLNESS I NOV. 2 MENTAL ILLNESS II/STREET DRUGS NOV. 3 MID TERM II , (Wed.) coverage to the end of Oct. 26 th NOV. 9 BRAIN CHEMISTRY NOV. 16 HORMONES NOV. 23 HEADACHES/COLDS/CAFFEINE NOV. 30 DRUG MARKETING/TOBACCO 4 4 2 mid-terms Oct. 4 th , Monday Nov. 3 rd , Wednesday 30% each + 40% final 6:15 - 8:30 seating/rooms-- later + questions from readings announced on the website
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2 5 preliminary perspectives OVERVIEW 6 “… way back when there weren’t that many problems with health .” March 12, 1989 6:40 am FM 93 Plattsburgh, N.Y . 7 David Teniers the Younger ~ 1670 8 Diagnosis by urine colour infection liver problems food or bleeding Vitamin B2 (riboflavin)
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3 9 9 10 10 147 11 At the end of the last century life expectancy for a man was about 47 years. Now it is overall over 80 for men and women with an edge to women. 12 12 Overall Life Expectancy (yrs) 2005-2010 data 1. Andorra 84 3. Japan 82 7. Australia 82 8. Canada 81 9. France 81 10. Sweden 81 13. Israel 81 50. USA 78 126. WORLD 67 137. Russia 66 194. Swaziland 40 + ~2 women - ~ 2 men
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4 13 % persons > 65 years 60 70 80 90 00 Æ 20 USA 9 10 11 12 12 16 Japan 6 7 9 12 17 28 W o r l d 5 6679 9 Over the years, she became the biggest attraction in Arles since Vincent Van Gogh's visit to the town in 1888. She met Van Gogh as a girl, when the artist came to shop at her father's art supplies store, and remembered him later as "dirty, badly dressed and disagreeable." Jeanne Calment, 122 14 Life Expectancy 1918 pandemic 15 DEATHS- WORLD INFECTIOUS DISEASES (millions) Respiratory 5 Diarrheal 3 Tuberculosis 3 HIV 3 Malaria 2 Hepatitis B 1 Measles 1 Tetanus 1 Whooping Cough Worms 16 pandemic 30 - 50 million - World
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5 sneeze screens 19 Bacterial pneumonia caused most of the deaths in the 1918 Flu. The pneumonia was caused when normal nose and throat bacteria invaded the lungs by a path created when the virus destroyed the bronchial cells. 20 From survivors - From blood samples from 32 survivors (91-101 in age) all reacted to the 1918 virus, suggesting they still had antibodies to the virus. The antibodies could be used for future outbreaks of flu strains similar to the 1918 virus.
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6 21 Eradication of Disease Many non-drug methods Smallpox (vaccination) 22 W orld H ealth O rganization- vaccinations have saved over 40 million in 20 years 23 Eradication of Disease Smallpox Polio Leprosy Guinea Worm Disease Chagas Disease 24 Eradicated in the Americas in 1991 Reduced world-wide to less than 4,000 cases
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7 25 Eradication of Disease Smallpox (eradicated) Polio (controlled) Leprosy Guinea Worm Disease Chagas Disease 26 27 28 Smallpox Polio Leprosy Guinea Worm Disease Chagas Disease “kissing bug”- a parasite-symptoms come after 10-20 years- fever-swelling Insecticide spraying is effective
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This note was uploaded on 09/29/2010 for the course SCIENCE 183 taught by Professor Harpp during the Spring '10 term at McGill.

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Drug History - Harpp The World of Chemistry 183 (170) DRUGS...

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