MCB 32 Lecture 3 - Molecular Cell Biology 32 Professor...

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Molecular Cell Biology 32 Professor Terry Machen 9/2/10 Lecture 3 ASUC Lecture Notes Online is the only authorized note-taking service at UC Berkeley. Do not share, copy, or illegally distribute (electronically or otherwise) these notes. Our student-run program depends on your individual subscription for its continued existence. These notes are copyrighted by the University of California and are for your personal use only. D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. Announcements Thursdays section 10 room has moved to 209 Dwinelle. Lecture Today’s topic is an overview on metabolism which includes glycolysis, krebs, and oxidative phosphoralation. You don’t need to memorize any structures involved. I will be showing videos today that will help you understand these pathways. ATP synthase moves around like a motor and smashes ADP into Pi to make ATP. It does this by using protons that move through the motor. YouTube video on animation of electron transport chain: Energy from organic molecule are stored as NADH, FADH2 which then give up their high energy electrons to the electron transport chain to generate a proton gradient in the mitochondria inner membrane space. This gradient will run the ATP synthase to produce ATP. (Will show full video next time) We use wind energy to create electricity. A dam uses water to spin turbines to generate electricity. All these examples take energy and store it as a different form. We take energy and convert it into molecular energy like ATP. Energy of the sun goes into plants and combines with CO2 and water and is stored as glucose. This is an anabolic process which means that it is forming more complex molecule by putting simple molecules together. This process is also endergonic which means that it requires energy. Humans take glucose which is 6 carbons and convert it to carbon dioxide and water. This reaction will release energy. There are many steps. In this process also known as glcolysis glucose is oxidized, which means that oxygen is added. This reaction is catabolic, which means that a complex molecule is broken down into simpler ones. This reaction is exergonic which means it releases energy. When a molecule is oxidized like glucose, a molecule must also be reduced. This occurs simultaneously. In metabolism O2 is ultimately reduced, which means that it gains an electron and in this process it forms water which is released. This will be discussed further later in the lecture. Coupling reactions
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This note was uploaded on 09/29/2010 for the course MCB 57703 taught by Professor Machen during the Fall '08 term at University of California, Berkeley.

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MCB 32 Lecture 3 - Molecular Cell Biology 32 Professor...

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