MCB 32 Lecture 6 - MOLECULAR CELL BIOLOGY 32 Professor...

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MOLECULAR CELL BIOLOGY 32 Professor Terry Machen 09/14/10 Lecture 6 ASUC Lecture Notes Online is the only authorized note-taking service at UC Berkeley. Do not share, copy, or illegally distribute (electronically or otherwise) these notes. Our student-run program depends on your individual subscription for its continued existence. These notes are copyrighted by the University of California and are for your personal use only. D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. Announcements The review session will be tonight (9/14) at 5-7pm in 2050 VLSB. I will give you a study guide for the midterm. Today we will be doing a lot of review with some new things. Lecture Today’s Schedule Membrane transport Uniport, symport and antiport Primary and secondary active transport Water transport by osmosis Transmembrane voltages Review: Nernst equilibrium potential – only one ion permeable Cells membranes permeable to many ions, V m E K or E Na Synapses and Integration Review of action potential propagation Transmitter release from presynaptic nerve in packets Action potential and Ca Vesicle release Neurotransmitter binds to receptor and depolarizes postsynaptic nerve EPSP = graded potential action potential triggered Neurotransmitter inactivated Integration of activities of multiple nerves Excitatory nerves depolarize, EPSP’s Inhibitory nerves hyperpolarize, IPSPS EPSP’s and IPSP’s can add temporal and spatial summation Membrane transporters: Uniporter often refers to facilitated diffusion. An example is the glucose transporter, which mediates glucose uptake from blood into the cell. Unitransporters mediate the transport of one molecule from high concentration to low concentration. Symporter, or cotransporter, carries at least two molecules in the same direction through a cell membrane. An example is the Na-coupled glucose uptake in the intestine lumen. The transporter takes Na and glucose together . It won’t take them separately. There are millions of these transporters in the intestine.
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MOLECULAR CELL BIOLOGY 32 ASUC Lecture Notes Online: Approved by the UC Board of Regents 9/14/10 D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. 2
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MCB 32 Lecture 6 - MOLECULAR CELL BIOLOGY 32 Professor...

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