Quiz 10 - facing surface proteins 3. Which type of receptor...

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1. What is the first step in sorting and retaining proteins from Golgi into COPII coated vesicles? A. The exterior COPII targets the vesicle to move away from the RER (anterograde) B. Soluble proteins (cargo) in the lumen bind to specific transmembrane cargo receptors which face the lumen of the RER. C. COPII proteins bind to the cytoplasmic part of the cargo receptor D. Clathrin binds to the cytoplasmic part of the cargo receptor, followed by the binding of COPII. E. Soluble proteins (cargo) in the cytoplasm bind to COPII on the cytoplasmic side of the vesicle. 2. How can soluble proteins in RER get targeted to go to another compartment? A. They don’t. Only membrane proteins move out of the RER B. By clathrin-coating the budding vesicles C. By binding to special transport COP proteins called t-SNARES D. By antibody interactions between transport vesicles and destination membranes E. By binding to transmembrane cargo receptors to sort them into transport vesicles which can be targeted to the proper destination by their externally-
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Unformatted text preview: facing surface proteins 3. Which type of receptor is needed to transport lysosomal enzymes through the endomembrane system to the lysosome? A. KDEL receptors B. Mannose-6-P receptors C. V-Snare D. SRP receptors E. LDL receptors 4. Lysosomes are: A. Acidified by a lysosomal membrane proton pump B. Filled with many enzymes that were made in the cytoplasm C. Mitochodrial inner membranes that are inside-out D. Vesicles that do not contain any glycoproteins E. Not part of the endomembrane system 5. The main purpose of receptor-mediated endocytosis is: A. To add plasma membrane during cell growth B. To make LDL (low density lipoproteins) C. To help make the VTC (vesicular tubular clusters) D. To aid in the transport of specific extracellular molecules into the cell E. To bring bacteria into the cell to be digested in autophagolysosomes Answers: 1. B 2. E 3. B 4. A 5. D...
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