Genetics380_Lecture3_2009_sakai

Genetics380_Lecture3_2009_sakai - 9/8/09 Genetics 380...

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9/8/09 1 Genetics 380 Lecture 3: Chromosomes and Cellular Reproduction Reading: Chapter 2 of textbook. Representative chromosomal landscapes The genomes of four different species have very different topographies. Light green, introns; dark green, exons; white, regions between coding sequence (including regulatory regions plus “spacer” DNA).
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9/8/09 2 In eukaryotes, DNA is complexed with histones to form chromatin. A virus is a simple replicative structure consisting of protein and nucleic acid.
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9/8/09 3 What evolved first: viruses or cells? Cell reproduction (mitosis) Copying genetic material Separating the copies Cell division Prokaryotic cells reproduce by simple division. Doubling time = 20 min. In 10 hours, one bacterium may produce a billion descendants.
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9/8/09 4 Eukaryotic cell reproduction Eukaryotic Chromosomes Each species has a characteristic number. •Diploid eukaryotic cells have two sets of chromosomes, organized as homologous pairs . Cells with a single set of chromosomes are haploid. A diploid genome visualized The nuclear genome in cells of a female Indian muntjac, a type of small deer (2n = 6). The six visible chromosomes are from a cell caught in the process of nuclear division. The thee pairs of chromosomes have been stained with chromosome- specific DNA probes, each tagged with a different fluorescent dye (chromosome paint). A nucleus derived from another cell is at the stage between divisions.
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5 Life cycle of a diploid animal Concept check Diploid cells have
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This note was uploaded on 10/03/2010 for the course RUT 146:356 taught by Professor Gol during the Spring '10 term at Rutgers.

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Genetics380_Lecture3_2009_sakai - 9/8/09 Genetics 380...

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