Chapter 4 part 2

Chapter 4 part 2 - Chapte 4: Part 2 r o o Prote 3-D...

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Chapter 4: Part 2 Protein 3-D structure: 3 o and 4 o structure and protein folding.
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3 o Structure third level of protein organization folding of polypeptide chain causes 2 o structures to interact Amino acids that are far apart in sequence end up close together permitting interactions of side chains….peptide chains folds due to these interactions which are primarily hydrophobic…can be some electrostatic interactions…and can be further locked in place by sulfide bridges formation of motifs and domains (supersecondary structures)
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Proteins with similar 1 o structure also have similar 3 o structure tuna 1 G DVA KG K K T F VQ KCAQCHTVE N GG K HKVGPNL W GLFGR KT GQAEGYSYTDANK S K G I VWN yeast 1 G SA KKG AT L FKT R C L QCHTVEKGG P HKVGPNL H G I FGR H SGQAEGYSYTDAN IK K N V W D E rice 1 G NP K A G E K I FKTKCAQCHTV D KG A G HK Q GPNL N GLFGR Q SG TTP GYSY S T ANK MAV IW E E tuna 61 E TL M EYL E NPKKYIPGTKM I F A G I KK KG ER Q DL V A YLK S ATS yeast 61 N N M S EYL T NPKKYIPGTKM A F G GLKK EK D R N DLI T YLK K A CE rice 61 NTL Y D YL L NPKKYIPGTKM V F P GLKK PQ ER A DLI S YLK E ATS
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Common Motifs combinations of α - helices, β -sheets and loops. Helix-loop-helix
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Chapter 4 part 2 - Chapte 4: Part 2 r o o Prote 3-D...

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