connective tissue problem set-1

Connective tissue - Justin Partridge Amanda Palffy Heather Quadir Problem Set Connective Tissue When a person reacts to an allergen IgE antibodies

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Justin Partridge Amanda Palffy Heather Quadir 10/7/10 Problem Set – Connective Tissue 1. When a person reacts to an allergen, IgE antibodies are secreted from lymphocytes. The IgE antibody binds to receptors on mast cells, causing degranulation, synthesis of leukotirenes, and the release of histamines. This leads to increased mucous production, bronchial constriction, and blood vessel dilation. Fluid will, therefore, concentrate in the nasal cavity and there will be a buildup of mucous causing the “stuffed up” symptom. 2. The reserves of white fat would remain around the body’s core and vital organs. This is because white fat is heavily vascularized and functions to store energy, insulate, and pad the body. The vital organs are most important and therefore it would be most crucial to maintain energy (breakdown of lipid droplet into fatty acids), heat, and padding around them. 3. Osteoclasts function to degrade bone. As new bone grows osteoclasts breakdown old bone in order to maintain space within the bone for bone marrow. Bone marrow is important because it creates erythrocytes in the blood and also produces immune cells for the body. If osteoclastes are defective, bone marrow will be reduced and production of erythrocytes and immune cells will be inhibited, resulting in fewer defenses against infection and anemia. 4. Normal bone lengthening takes place at the epiphyseal growth plate of long bones where a cycle of cartilage growth, matrix formation and calcification of cartilage occurs to successfully lengthen bones. This cellular cycle is known as endochondral ossification. After the bone collar and hyaline cartilage are formed to model the bone being made, the
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This note was uploaded on 10/06/2010 for the course ES ES271 taught by Professor Machaut during the Spring '10 term at Colby.

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Connective tissue - Justin Partridge Amanda Palffy Heather Quadir Problem Set Connective Tissue When a person reacts to an allergen IgE antibodies

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