glycolysis

glycolysis - 3. Phosphorylation C. Hexokinase vs....

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
BC368 – Biochemistry of the Cell II Carbohydrate Catabolism Topics: Readings in Lehninger I. Central Role of Glucose pp. 527-528 II. Glycolysis Pathway pp. 528-541 A. Purposes B. Types of transformations C. Reactions of Phase I (Preparatory phase) 1. Why phosphorylations at step 1? 2. Enzymes and irreversible reactions 3. “TIM” D. Reactions of Phase II (Payoff phase) 1. Covalent catalysis 2. Substrate-level phosphorylations 3. Role of BPG E. Efficiency F. General trends III. Fermentations pp. 542-546 A. Lactic acid B. Ethanol 1. Pyruvate decarboxylase and TPP 2. Alcohol dehydrogenase IV. Entry of Other Hexoses and Glycerol pp. 549-551 V. Glycogen Breakdown pp. 547-548 A. Glycogen phosphorylase B. Debranching enzyme VI. Glycolysis Regulation pp. 551-557 A. PFK-1 1. Allosteric inhibitors 2. Allosteric activators B. Pyruvate kinase 1. Allosteric inhibitors 2. Allosteric activators
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: 3. Phosphorylation C. Hexokinase vs. glucokinase VII. Regulation of Glycogen Metabolism pp. 557 VIII. Pentose Phosphate Pathway pp. 558-560 A. Makes NADPH and D-ribose-5-P B. Pathway ____________________________________ Some things to consider while youre reading: Glycolysis is probably the closest we will get to a truly universal pathway. It is the central metabolic pathway in a wide variety of organisms. Begin to consider what will happen to an individual if they are deficient in one of the enzymes in the metabolic pathways we discuss. Consider the effect on the intermediates in the pathway, on the pathway as a whole, and on the organism as a whole. Is it always a straightforward relationship?...
View Full Document

This note was uploaded on 10/12/2010 for the course BC BC367 taught by Professor Millard during the Spring '10 term at Colby.

Ask a homework question - tutors are online