11. bio214 genomics

11. bio214 genomics - Microbial Genomics Genomics in...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
Microbial Genomics
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Genomics in Medical Education “The explosion of information about the new genetics will create a huge problem in health education. Most physicians in practice have had not a single hour of education in genomics and are going to be severely challenged to pick up this new technology and run with it." Francis Collins
Background image of page 2
Genomics study of molecular organization of genomes, their information content, and gene products they encode
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Determining DNA Sequences Sanger Method uses dideoxynucleoside triphosphates (ddNTP) automated systems use dideoxynucleotides labeled with fluorescent dyes
Background image of page 4
- used as substrate by DNA polymerase - terminates DNA synthesis Dideoxyadenosine triphosphate
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
QuickTimeª and a decompressor are needed to see this picture.
Background image of page 6
Automated methods work on same principle as Sanger method but use fluorescent labels
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Whole-Genome Shotgun Sequencing developed in 1995 by J. Craig Venter and Hamilton Smith four stage process library construction generates clones of portions of genome random sequencing determines sequences of clones fragment alignment and gap closure annotation
Background image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 10/06/2010 for the course BIO 214 taught by Professor Dr.xinfan during the Spring '10 term at West Chester.

Page1 / 26

11. bio214 genomics - Microbial Genomics Genomics in...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online