BB lecture 10-26 glycolysis, citric ac. cy.

BB lecture 10-26 glycolysis, citric ac. cy. - Chapter...

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Chapter 9 (pp.165-170) – Aerobic Respiration (continued) Learning objectives • Recall the purpose for aerobic respiration; know the overall process and stages • Know what “goes in” and what “comes out” of the glycolysis pathway and Krebs cycle. Know where these occur. • Know the key regulatory step in glycolysis • Be able to identify where/how much ATP is derived from substrate phosphorylation rx. • Distinguish the different coenzymes involved in respiration
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The Stages of Cellular Respiration: A Preview Respiration is a cumulative function of three metabolic stages Glycolysis The citric acid cycle [aka Krebs cycle, aka TCA (tricarboxylic acid cycle)] Oxidative phosphorylation
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Glycolysis Means “splitting of sugar” Occurs in the cytoplasm
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Electrons carried via NADH Glycolysis Glucose Pyruvate ATP Substrate-level phosphorylation Electrons carried via NADH and FADH 2 Citric acid cycle Oxidative phosphorylation: electron transport and chemiosmosis ATP ATP Substrate-level phosphorylation Oxidative phosphorylation Mitochondrion Figure 9.6 Cellular respiration begins with Glycolysis What is …?
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Enzyme Enzyme ATP ADP Product Substrate P + ATP produced by Substrate-level phosphorylation Figure 9.7
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Glycolysis Means “splitting of sugar” Occurs in the cytoplasm Breaks down (oxidizes) glucose into pyruvate
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Examine the name of the enzyme and tell what it does: Hexokinase (hint: hexose kinase) Phosphoglucoisomerase (hint: phospho-gluco-isomerase) Phosphofructokinase (hint: phospho-fructo-kinase) Aldolase (hint: ald…) Isomerase (hint: isomer…)
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Figure 9.9 Glycolysis in 2 phases w/ 10 easy steps : Energy investment phase ( Layer 1 )
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Figure 9.9 Glycolysis: Energy investment phase ( Layer 2 )
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Figure 9.9 A closer look at glycolysis: energy payoff phase ( Layer 3 )
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Figure 9.9 A closer look at glycolysis: energy payoff phase ( Layer 4 )
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BB lecture 10-26 glycolysis, citric ac. cy. - Chapter...

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