Lecture 101 Chromosomes Chiu 2008

Lecture 101 Chromosomes Chiu 2008 - Chi-hua Chiu Dept of...

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Chi-hua Chiu Dept. of Genetics Office Hours: Tuesdays, 12:45-1:45 Douglass Campus MSLC Copy of important figures (not in your book) and lecture guide will be on reserve at the MSLC.
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How to get Powerpoint files (these are in pdf) ftp://lifesci.rutgers.edu/chiu-review username: chiuftp password: NelTMP604 (case sensitive!) look for General Biology Chiu folder click on the individual pdfs to download
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The Basic Principles of Heredity: Chromosomal Basis Chapter 11
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Chromosome theory of inheritance To explain patterns of inheritance, it is inferred that genes (loci) are arranged in specific locations along a chromosome in a linear manner.
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Independent Assortment
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B = normal gray body (wild type) b = black body V = normal long wing (wild type) v = vestigial (short) wing Fig. 11-11
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Crossing-Over Fig. 11-12 Recombinant-type gametes result from crossing over in Meiosis I
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B = normal gray body (wild type) b = black body V = normal long wing (wild type) v = vestigial (short) wing Fig. 11-11
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Calculating frequencies Total number of offspring = 2300 Number of individuals with genotypes that match parental gametes: 1150 1150/2300=0.5=50% Number of individuals with genotypes that are recombinant gametes: 1150 1150/2300=0.5=50% In this particular case, we infer genes are unlinked .
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Alleles of loci that are on the same pair of homologous chromosomes – do not undergo independent assortment.
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