Microbial Growth - Microbial Growth Growth: an increase in...

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Microbial Growth Growth : an increase in the number of cells Wide variety of chemical reactions Energy transformations Synthesis of monomers Polymerization of macromolecules Formation of cellular structures Binary fission
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Population Growth Growth : increase in numbers, mass Growth rate Generation Generation time (doubling time) Exponential growth
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Binary Fission
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The Fts “Filamentous temperature sensitive” Universal in prokaryotes Found in mitochondria, chloroplasts Divisome = division apparatus Multiple proteins involved FtsZ proteins mark division plane Shows structural tubulin Targets for antimicrobials
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“Filamentous temperature sensitive”
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Occurs prior to FtsZ ring formation Cessation triggers FtsZ ring formation (?) FtsZ ring forms between the two nucleoids FtsK mediates separation of chromosomes
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Appearance & Breakdown of Ftz Ring
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Cell Shape & Actin-Like Proteins in Prokaryotes Specific proteins define bacterial shapes Significant homology to actin MreB forms actin-like cytoskeleton In Bacteria ( Archaea?) Filamentous, spiral-shaped bands Coccus is a default shape
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Rothfield et al., ASM News , 2005
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Growth Rate of a Microbial Culture
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Growth Cycle Of Populations Lag phase Seen with old inoculum Damaged cells Transfer from nutrient-rich to nutrient-poor media Exponential phase Cells in healthiest state Mid-exponential cells Rates of exponential growth can vary
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Microbial Growth - Microbial Growth Growth: an increase in...

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