BIO 320 2009 Fall Exam 2 Key

BIO 320 2009 Fall Exam 2 Key - BIO 320 Dr. Bushart Print...

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BIO 320 Dr. Bushart Print Name:__________Key_________________ Midterm Exam #2 2 PM Thursday October 8, 2009 General instructions: Read each question carefully and don’t hesitate to ask if a question seems unclear. Trying to provide an answer for every question is advantageous; you will not be penalized for guesses. The short-answer questions have speciFc answers, although for some, more than one answer is possible. If possible, answer each question in the space provided, but if needed, continue on the back. If you use a diagram as part of your answer, be sure to also include appropriate labeling and/or a short written explanation. To receive full credit you must clearly and fully answer the question being asked. Partial credit may be given in 0.5 point increments. This exam is worth 100 points (the points for each section/question are noted in parentheses). Use pen if you want a chance for a regrade. Short answer (99 points +1 freebie): There are 8 short-answer questions over 3 pages. Write a clear concise answer for each question. Some questions may have more than one possible answer but require you to defend your choice. Be sure you include clear explanations. Make sure your response answers the question being asked! 1. Certain molecules can travel from extracellular spaces to the nucleus in order to alter gene expression. Explain why a molecule like this might need to be handled by two distinct transport systems. (This has to do with equivalency of spaces and can be determined by considering if a membrane has to be crossed or not.) There are two distinct spaces involved in this process. The inside of the nucleus is equivalent to the cytosol, so the molecule would Frst need to get to the cytosol by crossing a membrane (transport system #1) and then transition between the equivalent spaces of the cytosol and nucleus (transport system #2). [System #2 is speciFcally gated transport.] 2. Identifying the function of new proteins can be aided by understanding their localization. If we examine proteins isolated from whole living cells, we should be able to identify NLS sequences from nuclear proteins. However, for identiFcation of mitochondrial proteins we would need to examine gene
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BIO 320 2009 Fall Exam 2 Key - BIO 320 Dr. Bushart Print...

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