Part 1:(21 points, correct elimination 4 points, incorrect elimination –21 points). The following properties apply to the circuit shown below. ¾ Cell F has no spontaneous activity ¾ Cell F does NOT habituate ¾ Cell F has post-inhibitory rebound (through the cell E to Cell F synapse) ¾ Cell E has spontaneous activity ¾ Cell E habituates through the Cell D to Cell E synapse ¾ This habituation is through the D ÆE synapse so the longer D is on the less effective Cell E’s excitatory neurotransmitter receptor becomes ¾ Cell E does NOT have has post-inhibitory rebound ¾ Cell F’s inhibition onto cell E can completely shut down cell E including inhibiting and turning off spontaneous spikes ¾ Cell E’s spontaneous firing is at a low enough rate that it cannot counteract Cell D ÆF excitation ¾ D ÆF is a shorter length than D ÆE Which of the following can be the activity pattern of the circuit, when D fires as shown in the panels. Excitation Inhibition LEGEND(1) (2) (3) (4) (5) (6)
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