16 exchange across capillary wall

16 exchange across capillary wall - 16 exchange across a...

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16. exchange across a capillary wall I. Capillary a. Anatomy- specialized to allow transport i. Walls- 1 micron thick- endothelial cell thick ii. Tight junction- between endothelial cells iii. Forms pores that small molecules go through 1. Water, electrolytes, small water soluble molecules 2. Proteins don't cross iv. Tightness of tight junction 1. Blood brain barrier- water cant cross 2. Muscles- tight- water cross ok, proteins- poor crossing 3. Kidneys- water, small proteins cross v. Diameter 1. Arteriole- 5 microns, venous- 9 microns 2. Red blood cells- 8 microns- need to squeeze b. Transport mechanism i. Diffusion- follows concentration gradient 1. Lipid solubles- through cell membrane a. O2 and CO2 2. H2O solubles a. Go through tight junction- H2O pores b. Small- glucose, eletrolyte, etc ii. Large molecules- too big and slow fusion 1. Proteins use vesicle transport iii. Filtration 1. Pushes H2O through 2. H2O transport- through tight junction 3. Carries small H2O soluble molecules c. Forces out (Pc + pi of i)
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This note was uploaded on 10/14/2010 for the course BIOLOGY bipn 100 taught by Professor Armour during the Spring '10 term at UCSD.

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16 exchange across capillary wall - 16 exchange across a...

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