electrolyte balance

electrolyte balance - 18. Fluid/ Electrolyte balance I. ADH...

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18. Fluid/ Electrolyte balance I. ADH a. Control i. Osmolarity of plasma- osmoreceptors in hypothalamus 1. Threshold- 280mOsm triggers ADH release ii. BP/BV 1. Stretch receptors- atrial wall/ baroreceptors- aorta/ carotid sinus a. Increase ADH release iii. Others 1. Exercise increase ADH 2. Ethanol, ANP decrease ADH b. Mechanism- vasopressin (V1/V2) i. V1- Gq- vasoconstriction- blood vessels ii. V2- Gs- releases vesicle with Aquaphorin 2- allows water to go through and be reabsorbed c. Function i. H2O reabsorption (-) [osm] plasma- increase BV/BP ii. Urine concentration (+) osm urea iii. End of DT urine is dilute iv. No ADH urine is dilute v. With ADH urine is concentrated vi. Max [osm]urine [osm] medulla driving force for secretion II. Renin-Angiotensin-Aldosterone (RAAS) a. Anatomy i. Glomerulus near distal tubule 1. Cells near glomerulus- juxtaglomerulus cells 2. Cells near distal tubule- macula densa cells a. Together they are the juxtaglomerular apparatus
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This note was uploaded on 10/14/2010 for the course BIOLOGY bipn 100 taught by Professor Armour during the Spring '10 term at UCSD.

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electrolyte balance - 18. Fluid/ Electrolyte balance I. ADH...

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