percent and ratio _2_

percent and ratio _2_ - Percentage/Ratio Strength PRACTICE...

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Unformatted text preview: Percentage/Ratio Strength PRACTICE PROBLEMS 1. A pharmacist received the following prescription: Phenobarbital Elixir 15 ml Belladonna Tincture 25 ml Aromatic Elixir 60 ml Purified water q.s. 100 ml Sig. One tsp. b.i.d. If Phenobarbital elixir contains 0.5 % of phenobarbital, how many milligrams of phenobarbital would be taken daily? 2. How many milligrams of cocaine should be used in compounding the following prescription? Cocaine 0.2% Mineral oil ad 50 g Sig. Nasal spray 3. How many grams of potassium iodide are represented in each dose of the following prescription? Sol. Potassium Iodide 50% 30 ml Sig. 1 ml in 10 ml of water a.c. 4. How many grams each of iodine and potassium iodide should be used in compounding the prescription? Iodine 1% Potassium Iodide 2% Glycerin ad 500 g 5. Methotrexate sodium injection contains 25 mg of methotrexate sodium per milliliter. What is the percent concentration of methotrexate in the injection? 6. How many milligrams of salicylic acid and how many milliliters of resorcinol monoacetate should be used in compounding the prescription? Salicylic acid 0.1% Resorcinol Monoacetate 3% Isopropyl Alcohol ad 250 ml Sig. For the scalp. 7. Paregoric contains the equivalent of 0.4% opium. How many milligrams of opium are represented in a tablespoonful dose of a mixture of equal parts of paregoric and Kaopectate? 8. Belladonna leaf contains 0.3% of alkaloids. If 10 g of leaf are used to prepare 100 ml of Belladonna tincture, how many milligrams of alkaloids are contained in this volume of the tincture? PHCY 6106-Teixeira 1 Percentage/Ratio Strength PRACTICE PROBLEMS 9. One liter of Purified water is mixed with 5 Lb.. (1 Lb.=454 g) of wool fat. Calculate the percentage (w/w) of purified water in the finished product. 10. What is the percentage strength (w/w) each of Iodochlorhydroxyquin and Hydrocortisone in the prescription? Iodochlorhydroxyquin 0.9 g Hydrocortisone 0.15 g Cream base ad 30 g 11. How many grams of salicylic acid and how many milligrams of menthol should be used in compounding the prescription? Salicylic acid 2% Menthol ¼% Talc ad 60 g 12. From the following formula calculate the quantity, in grams, of each ingredient, required to prepare 250 suppositories : Benzocaine 0.8% Ephedrine sulfate 0.2% Zinc oxide 4% Camphor 2.1% Cocoa butter ad 2g 13. Phenobarbital Elixir 60 ml Aludrox Suspension 180 ml Sig. Two teaspoonful t.i.d. If Phenobarbital elixir contains 0.4% of phenobarbital, a) How many milligrams of phenobarbital would be contained in each dose of the prescription? b) How many grams of phenobarbital would be taken if the prescribed dosage regimen were followed for 1 week? 14. Plasma protein fraction (PPF) is available as a 5% (w/v) solution. If the dose of the solution for a child is given as 5 ml per Lb., how many grams of PPF would be administered to a child weighing 20 kg? (1 kg=2.2 Lb.) 15. A vaginal foam contains 0.01% (w/v) of dienestrol. Express this concentration as a ratio strength. 16. A tetracycline syrup is preserved with 0.08% (w/v) of methylparaben, 0.02%(w/v) of propylparaben and 0.10% (w/v) of sodium metabisulfite. Express these concentrations as ratio strengths. PHCY 6106-Teixeira 2 Percentage/Ratio Strength PRACTICE PROBLEMS 17. An injection contains 5 mg/ml (w/v) of lidocaine hydrochloride and 25 μg/ml (w/v) of epinephrine. Express the concentration of lidocaine hydrochloride as a percentage and that of epinephrine as ratio strength. 18. A sample of white petrolatum contains 10 mg of Tocopherol per kg as a preservative. Express the amount of tocopherol as a ratio strength. 19. Dibucaine Hydrochloride solution is used for spinal anesthesia in a concentration of 1:1500 (w/v). How many milligrams of dibucaine hydrochloride are contained in a 20 ml vial of the solution? 20. What is the concentration (percentage and ratio) of Epinephrine in the following compounded prescription? Epinephrine solution 1:1000 7.5 ml Simple syrup ad 60 ml 21. A hospital pharmacist adds 10 ml of a 20% (w/v) solution of potassium iodide to 500 ml of D%W for parenteral infusion. What is the percentage strength of potassium iodide in the infusion solution? 22. Insulin injection is preserved with 0.25% (w/v) of meta-cresol. a) Express this concentration as a ratio strength. b) Calculate the quantity, in milligrams, of meta-cresol in a 20 ml vial of the injection. 23. If a dry powder mixture of the antibiotic Amoxicillin is diluted with water to 80 ml by a pharmacist in order to prepare a prescription containing 125 mg Amoxicillin per 5 ml, a) How many grams of Amoxicillin are there in the dry mixture? b) What is the percentage strength of Amoxicillin in the filled prescription? 24. How many milliliters of a 70% (w/w) solution having a specific gravity of 1.2 will be needed to prepare 600 ml of a 10% (w/v) solution? 25. If 10 ml of a Nitroglycerin injection (5 mg of nitroglycerin per ml) is used to make a liter of an intravenous fluid, what is the percentage strength (w/v) of Nitroglycerin in the final product? 26. How many milligrams of gentian violet should be used in preparing the following solution: Gentian violet solution 1:10,000 (w/v) 500 ml Sig. Instill as directed. PHCY 6106-Teixeira 3 ...
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