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Sleep 2010 - Sleep and its Disorders(Chapter 10 pp293-294 1...

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Sleep and its Disorders (Chapter 10, pp293-294) 6. Arousal/Sleep systems and the roles of neurotransmitters 1. How do we record sleep? 2. Stages of sleep 4 . How does sleep change with age ? 5. Theories of sleep 3. What makes us fall asleep? For interest… what do sleep stages look like?
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1.Recording of Sleep Electroencephalograph (EEG) Electrooculograph (EOG): eye movement Electromyograph (EMG): muscle tone And for clinical studies: Electrocardiograph (ECG), tibialis EMG, respiratory movement , oxygen saturation (SaO 2 ) EEG, EOG and EMG, together, known as polysomnograph EEG measures voltage generated by excitation of the dendrites of the pyramidal cells in the cortex
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2. Stages of sleep : 2 major sub-divisions (REM and Non-REM) Stage 1 – transition stage? Stage 2 – light sleep Stage 3 deep sleep Stage 4 – deep sleep a. REM – rapid eye movement sleep (do most of our dreaming) b. NonREM (NREM): Stages 1-4 As we fall asleep, we enter: and then after about 90 minutes, enter first REM period Known as slow wave sleep (SWS) Together, these sleep stages are called a sleep cycle
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Sleep affected by three components: 1. Homeostatic pressure : 2. Circadian rhythm Need for sleep increases with increasing wakefulness Normally, fall asleep as body temperature drops Wake as temperature rises The sleep/wake cycle is correlated with core body temperature Ques: Think about homeostatic and circadian pressures - Why is shift work problematic?
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