Endocrinology Beginning Notes

Endocrinology Beginning Notes - E ndocr i nol ogy 1. 2. 3....

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Endocrinology 1. Brief History 2. What constitutes an endocrine system? 3. Endocrine Organs 4. Endocrine Pathways 5. Hormone Production 6. Secretion
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An Endocrine System A detailed understanding of an endocrine system will include an understanding of: 1. Anatomical description of cells producing hormone, target cells and their environment and distance of separation 2. Chemical structure 3. Details of hormone biosynthesis 4. How hormone gets to target cell 5. Detailed mechanism of how target uses receptors to detect hormone 7. How target communicates with hormone-producing cell to indicate an adequate presence of hormone (feedback loops)
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What is a hormone? Broad Definition:
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Hypothalamus – releasing factors ( newest ) Pineal Gland – melatonin Pituitary Gland (hypophysis) Adenohypophysis or Anterior Pituitary (LH, GH, TSH…) Neurohypophysis or Posterior Pituitary (VP, OX) Thyroid Gland (Thyroid hormones, Calcitonin) Parathyroid Gland (PTH) Fat (Leptin) Heart (Atrial Natriuretic Peptide) What are the known Endocrine Organs and their Products?
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Skin (Vitamin D) Gastro-entero-pancreatic System Stomach (Gastrin) newest Intestine (Secretin) Pancreatic Islets (Insulin, glucagon) Adrenal Gland (Epinephrine, Corticoids ) Kidney, Liver (Renin-angiotensin; Vitamin D 3 ) Testis (Testosterone, Inhibin) Ovary (Estrogen, Progesterone) Placenta (Chorionic gonadotropin)
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Modern Classification of Hormonal Communication Systems 1. Systemic
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Modern Classification of Hormonal Communication Systems 1. Paracrine
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Modern Classification of Hormonal Communication Systems 3. Autocrine
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Modern Classification of Hormonal Communication Systems 4. Neurohormones
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Modern Classification of Hormonal Communication Systems 5. Pheromones
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Peptide hormone production preprohromone
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Peptide Hormone production
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Steroid Hormone Production
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This note was uploaded on 10/14/2010 for the course ZOO 4125 taught by Professor Flanigan during the Fall '10 term at Wyoming.

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Endocrinology Beginning Notes - E ndocr i nol ogy 1. 2. 3....

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