Receptors

Receptors - 5.2 Know how cAMP production induces cellular...

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Receptors– Objectives and Study Guide (see Chapters 5 and 8) Overall aim : To achieve a fundamental understanding of the basis of the physiological environment, how non-permeable peptides transmit their signals to cells, Specific objectives: 1. Know that the receptor, not the ligand, determines the response in a specific cell. 2. List the 5 different types of receptor 3. Define the term genomic 4. Describe the effect of a ligand on a G-protein-coupled receptor with an unknown Effector 5. Describe the effect of a ligand on a G-protein-coupled receptor when adenylate cyclase is the effector 5.1 Define cAMP, protein kinase A (PKA), CREB, CRE, phosphodiesterase
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Unformatted text preview: 5.2 Know how cAMP production induces cellular responses 5.3 Know how phosphodiesterases work 5.4 Know what will happen if phosphodiesterases are inhibited (methylxanthines, ) 6. Describe the effect of a ligand on a G-protein-coupled receptor when phospholipase C is the effector 6.1 Know the IP 3-endoplasmic reticulum-Ca++ pathway 6.2 Know the diaglycerol (DAG)-protein kinase C pathway Important: Remember that you should also be able to answer the questions posed to you in Laboratory and be able to understand and apply the concepts behind the questions in Tutorial Sessions....
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This note was uploaded on 10/15/2010 for the course ZOO 3115 taught by Professor Flanigan during the Spring '10 term at Wyoming.

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