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Unformatted text preview: Draw Mechanism Clicker Quiz O Cl NH 2 Exam is Wednesday Evening It will cover Organometallics and Chapters 16 and 17 Draw a mechanism and predict product O Cl NH 2 Which of these structures is part of the mechanism? N O O OH H Cl Cl Cl N H H Cl N H H 2 N A B C D Draw a mechanism and predict product O Cl NH 2 What is the final product? N O N N Cl i ii iii N H N H NH 3 Cl A i B ii C iii D i + ii E i + iii F ii + iii G i + ii + ii i O NH O O Cl NH 2 Cl N H H N H H NH 2 Amides synthesis. O N H + N H H H Cl Use two moles of amine. One to make amide. One to react with HCl. Or you can add some other sacrificial base like pyridine. O O H O O Cl Cl O H B O BH + Cl- B What is B? B could be excess alcohol or some solvent molecule or an Adding base added base like pyridine. can change the mechanism. O H Cl O C O O O N Cl N N O N O H H O NH O O Cl NH 2 Cl N H H N H H NH 2 Amides are also similar. O N H + N H H H Cl Use two moles of amine. One to make amide. One to react with HCl. Or you can add some other base. O...
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This note was uploaded on 10/18/2010 for the course CHE 326 taught by Professor Fowler during the Fall '08 term at SUNY Stony Brook.
- Fall '08