lecture_11 - Gastrulation of A Frog Embryo Formation of the...

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Gastrulation of A Frog Embryo
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Iris Lens Retina Photoreceptors Cornea Fully formed eye Optic Nerve Future lens Future retina Brain Connection to brain Induction of the lens by retina Induction of the cornea by lens Future retina Future Cornea Future lens Non-neural ectoderm Neuroectoderm Formation of the neural tube Formation of the Vertebrate Eye
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Comparative Eye Development Fly Vertebrate Squid
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Is Eyeless/Pax6 a Master Gene for Eye Development? Arguments in Favor : Wild-type Wing 1) Decreased activity of pax6 genes results in reduced eye size in flies, mice, and humans. 2) pax6 genes are expressed in the early eye primordia of flies, humans, and squid, in which eyes were thought to have evolved independently. Wing Mis-expressing Human pax6 gene Eye 3) Mis-expression of fly or human pax6 genes in certain fly tissues (e.g. wing) result in formation of ectopic eyes.
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Is Eyeless/Pax6 a Master Gene for Eye Development?
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lecture_11 - Gastrulation of A Frog Embryo Formation of the...

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