Problem_Set_2008

Problem_Set_2008 - BILD7: Problem Set 1. What is the...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
BILD7: Problem Set 1. What is the general structure of DNA? 2. What did Chargaff discover and why was this important? 3. What was the major contribution of Rosalind Franklin? 4. How did solving the structure of DNA immediately suggest (1) how genetic information is copied every time a cell divides and (2) how genetic information in DNA is stored? 5. What was the major conclusion from the “Gurdon” experiment? 6. The “central dogma” of molecular biology says that “DNA makes RNA makes protein”. What exactly does this mean? 7. What happens during “transcription”? 8. What is the difference between RNA and DNA? (hint: what are the structural differences between RNA and DNA, where is RNA made? where does RNA function?). 9. What happens during “translation” and where in the cell does it occur? 10. During translation, is the genetic code read one, two, or three bases at a time and why? 11. Briefly describe an experiment, using DNA and bacteria, that demonstrates that DNA carries the genetic material. 12. Genes can generally be described as having two distinct parts. What are they? 13. Why is the sequence of amino acids that makes up a protein important? 14. Where is the “code” that determines the sequence of amino acids that makes up a protein? 15. What is a mutation? How can it cause a protein to lose its normal function? 16. What is meant by the statement “the genetic code is universal”? 17. What is Gregor Mendel best known for?
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
18. What is the difference between genotype and phenotype? 19. Define the following: allele, homozygous, heterozygous, dominant, recessive. 20. Assume that “+” is a dominant functional allele required to make pea seeds round, and “w” is a recessive allele that makes pea seeds wrinkled. What are the ratios of the genotypes and the phenotypes of the F1 progeny from the following crosses: (A) +/+ X w/w (B) +/w X w/w (C) +/w X +/w (D) w/w X w/w 21. You are given a vial of red-eyed flies in which all of the flies look normal (that is, they have no visible abnormalities). You are told that these flies are “carriers” for a mutation ( white ) that causes eyes to appear white. What GENETIC experiment could you do to prove that they are indeed “carriers” of the white mutation? 22. What are the two major parts of a typical gene? 23. Explain what is meant by the term “mis-expression of a gene”. What can a researcher learn from mis-expressing a gene? 24. What is a transcription factor and what does it do? 25. In general terms, how do cells communicate with one another? (hint: e.g. via signals and receptors) 26. What is the difference in effect between a signal that is secreted versus one that is tethered to the cell? 27.
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 9

Problem_Set_2008 - BILD7: Problem Set 1. What is the...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online