LECTURE 9 BILD1 S10 - ANNOUNCEMENTS Do homework on website...

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1 ANNOUNCEMENTS Do homework on website for preview of Exam questions! Midterm Exam #2 next Wednesday, May 5th in class - Review Session Monday, May 3rd, 6:30 PM, Pepper Canyon Hall 109 - Exam covers Chapters 8,9,10,12,13 (lectures 6-10). - Extra TA Office Hours tomorrow Thurs. - next Wed., as posted Midterm Exam #1 regrades will be returned next Monday Lecture 9: April 28, 2010 Cell Cycle Results in cell division into 2 genetically identical cells. Cycle alternates between Interphase and Mitotic phase. Cycle is regulated by molecular control system. Why is Cell Division so important? In Unicellular organisms – Reproduction In Multicellular organisms – Development – Tissue renewal 20 µ m 200 µ m sand dollar embryo after fertilization, forming two cells. Dividing blood cells Figure 12.2
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2 Overview of Cell Division 1. DNA duplication ( Replication ) 2. Chromosome condensation 3. Division of chromosomes into 2 nuclei ( Mitosis ) 4. Division of the cytoplasm into 2 cells ( Cytokinesis ) All steps are highly regulated to ensure precise cell division, resulting in two identical daughter cells Overview of Cell Division (1) DNA Duplication All of the cell’s DNA must be copied in order to distribute one genome to each daughter cell. ( Replication discussed in Lecture 12) Genome total DNA containing an organism’s complete set of genes Bacterial genome 4.6 x 10 6 base pairs ( E. coli ) Fruitfly genome 1.2 x 10 8 base pairs Human genome 3.3 x 10 9 base pairs Chromosome 1 unit of double-stranded DNA; 1 set
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LECTURE 9 BILD1 S10 - ANNOUNCEMENTS Do homework on website...

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