Lecture8_BILD 7_4_23_09

Lecture8_BILD 7_4_23_09 - Quiltwork Assembly of a Fly Head...

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Head Tail T1 T2 T3 A1 A2 A4 A5 A6 A7 A3 A8 Metamorphosis Quiltwork Assembly of a Fly
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Outline of Vein Development M L1 L2 L3 L4 L5 3rd Larval Instar Early Pupa M L1 L2 L3 L4 L5 L6 sCo Mid-Pupa->Adult
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L1 L2 L3 L4 L5 M Fly Wing
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L2 L3 L4 L5 sal Determining the Positions of Veins hh L2 dpp A P En En -> Hh -> Diffuses -> in A/P Organizer Dpp Dpp -> Diffuses -> -> L2 vein A P L5 L3 L4 L3 L4 Organizer A/P L2 L3 L4 L5
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hh- mutant L2 L3 L4 L5 WT L2 L3 L4 L5 hh dpp Mutant with reduced function A P En L3 L4 Hh Determines Positions of L3 and L4 Veins A P En L3 L4 En -> Hh -> Diffuses -> in A/P Organizer
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dpp- mutant L2 L3 L4 L5 L2 Dpp A P L5 sal L3 L4 Mutant with reduced dpp function WT L2 L3 L4 L5 L2 Dpp A P L5 L3 L4 Dpp -> Diffuses -> -> L2 vein Dpp Determines Positions of L2 and L5 veins
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Veins Form At Boundaries Along the A/P Axis L2 L3 L4 sal Dpp A P Dpp -> Diffuses -> -> L2 vein L5 + En hh dpp A P Organizer A/P En -> Hh -> Diffuses -> in A/P Organizer
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sal Dpp A P Dpp defines anterior border of domain + En hh dpp A P En-5 defines position of
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Lecture8_BILD 7_4_23_09 - Quiltwork Assembly of a Fly Head...

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